The multiple forms of α-D-mannosidase in human plasma
نویسندگان
چکیده
منابع مشابه
Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells.
Lysosomal α-D-mannosidase is an exoglycosidase involved in the ordered degradation of N-linked oligosaccharides. It is ubiquitously expressed, although the main transcript is more abundant in peripheral blood leucocytes. Here we report that α-D-mannosidase enzyme activity is very high in the promyelocytic leukaemia cell lines HL60 and NB4, as compared with other leukaemic cell lines or cells fr...
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We have previously reported the occurrence and partial characterization of a novel a-D-mannosidase activity on rat sperm plasma membranes [Tulsiani, Skudlarek and OrgebinCrist (1989) J. Cell Biol. 109, 1257-1267]. Here, we report the presence of a similar a-D-mannosidase activity in a soluble form in rat epididymal fluid. The soluble enzyme was purified nearly 500-fold with 9-12o% recovery to a...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1979
ISSN: 0264-6021
DOI: 10.1042/bj1790583